What is Transperineal Prostate Biopsy Surgery?

A transperineal prostate biopsy is a procedure where multiple biopsies of the prostate are taken via the perineal skin (between the scrotum and anus). The small samples of prostate tissue are collected using a biopsy needle and sent to a pathologist to be assessed microscopically.

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TransPerineal Prostate biopsy surgery video

Transperineal Prostate Biopsy Surgery - who is it for?

Who Is Transperineal Prostate Biopsy Surgery For?

A urologist will request a biopsy of the prostate gland for a patient when there is a suspicion of prostate cancer following blood tests and prostate-specific antigen (PSA) exams.

What are the benefits?

Ultrasound probes passing through the rectum ensure quality imaging of the region is captured. Compared to biopsies collected via the rectum, biopsies taken through the perineal skin rarely result in an infection since the skin of the perineum can be easily disinfected during surgical preparation ahead of the operation.

What happens During Surgery?

You will need to fast prior to your procedure.
A general or spinal anaesthetic will be administered before surgery commences.
Next the ultrasound probe will be inserted into the rectum, with a biopsy guide placed over the skin over the perineum.
A core biopsy needle will then be inserted through this skin.
The needle will be guided to the target area with the assistance of the ultrasound probe.
A core biopsy will then be taken.
This process will be repeated until a tissue sample has been collected from all areas of the prostate.

How long will I stay in hospital?

A transperineal prostate biopsy is a day surgery and patients can return home the same day.

What is my recovery time?

You will spend a short period of time in recovery after surgery to allow the anaesthetic to wear off. Your surgeon will come to discuss findings and arrange a follow up appointment. The surgery team will confirm that you are able to urinate before allowing you to be discharged. You will not be able to drive under the influence of the anaesthetic so please arrange from someone to take you home.


Pain, discomfort and bruising may be present in and around the perineum after the operation. A stinging sensation and some blood is to be expected when urinating. These symptoms will usually settle within 24-48 hours. Over the counter medication may help to alleviate pain. It is recommended that a minimum of two days be taken off work following the procedure.

SURGERY - criteria

Do you qualify for This Self Pay Procedure?

You are suitable for this surgery if:

  • You are over 16 years of age
  • You are not pregnant
  • You do not require complex rehabilitation or have a chronic disease that would require immediate post-operative care in an intensive care unit
  • You do not have sickle cell anaemia, renal failure or have had a cardiac arrest or cardiac intervention (e.g. insertions of stents) in the last six months
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